Frequency and Antibiotic Resistance Profile of Uropathogens Associated With Community Acquired Urinary Tract Infections

Abstract Background Community acquired urinary tract infections (CAUTIs) are among the most common bacterial diagnosed in community health practice resulting high rates of morbidity and economic costs associated with its treatment. CAUTIs usually treated empirically. Geographical variations etiologic agents their antibiotic sensitivity patterns common. Knowledge resistance trends is important for improving evidence-based recommendations empirical treatment UTIs. Adequate can cause decrease unnecessary hospital stays, cost, side effects as well reducing antimicrobial spread. Aim Work To determine implicated uropathogens community-acquired UTIs respective pattern to improve efficacy this infection. Patients Methods This a cross-sectional descriptive study conducted from November 2018 2019 at main Microbiology Lab Clinical Pathology Department, Ain Shams University Hospitals. Samples were received patients attending different outpatient clinics Hospitals having UTI symptoms whose urine samples showed significant growth (≥105 CFU/mL) pyuria (more than 8–10 pus cells by microscopic analysis) nitrite leukocyte esterase positive chemical analysis strip. Results A total 1600 who fulfilled our inclusion criteria sampled. Of these, 1058 had that while about 34% contaminated excluded . samples, 764 (72.21%) females 294 (27.79%) males female male ratio 2.6:1. Escherichia coli was found dominant bacteria prevalence rate 24.4% followed Klebsiella pneumoniae (13.8%). Tetracycline resistant 929 (95.4%) Ampicillin, Tazobactam-piperacillin, Ampicillin- sulbactam 90.1%, 81.7% 77.7% respectively; however, sensitive antibiotics against all Carbapenems (Ertapenem 72.9% fol Imipenem 66.5% Meropenem 66.4%) Nitrofurantoin Amikacin showing 64.3% 58.01% respectively However, For gram uropathogens, Linezolid highest 84% isolates. Conclusion The present reveals familiar respect species involved infections, however considerable empirically prescribed antibiotics.